Truckers 4 Hope is a 3-day, non-judged, Semi Truck Show with a variety of different activities for everyone to enjoy all weekend long. Truckers 4 Hope benefits Cystic Fibrosis Research and Hope 4 Hayze. Cystic Fibrosis (CF) is a life-threatening genetic disease that affects the lungs and digestive systems of approximately 30,000 children and adults in the United States.